Abstract
Background: Acute kidney injury (AKI) is very common, approximately 1/3 cases in Acute decompensated heart failure (ADHF), increasing the risk of cardiovascular events in the hospital and after discharge. The pathogenesis of AKI is complex, thus leading to many heterogeneous contexts and characteristics.
Objectives: Evaluate the frequency, characteristics of acute kidney injury and its risk factors in patients with acute decompensated heart failure.
Methods: Study design: a cross-sectional descriptive study, including 124 inpatient-treatment ADHF patients at Hue Central Hospital from January, 2022 – March, 2023. Data concerning characteristics of demographic, medical history, precipitating factors, and clinical symptoms, laboratory testing and treatment. Using analyzing multivariate Logistic to find risk factors for AKI.
Results: The mean age was 67,6 ± 17,07 years, the rate of male and female was equivalent. There were 38.7% of patients with AKI. Among them, the majority of RIFLE R classification with 52.1%, early onset before 48 hours accounted for 75% cases, the rate of recovery of kidney function before discharge was 68.1%. The risk factors for AKI when analyzing multivariate Logistic including Age (OR=1,02), NYHA Classification (OR=2,41), Creatinin at adminision (OR=1,05), NT-proBNP (OR= 1,057), GOT > 3 times (OR=7,3), and hyponatremia (OR=4,21).
Conclusion: AKI is common in ADHF. However, the characteristics of AKI are extremely diverse, expressed through the time of appearance, classification, and wheter recovery or not before discharge. Based on clinical and simple tests, it is possible to predict patients at risk of developing AKI.