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CA LÂM SÀNG Issue: Số 121 - 2026 TIM MẠCH CAN THIỆP

Percutaneous Intervention for Late Recanalization After Atrial Septal Defect Closure

Đỗ Quốc Hiển: Bệnh viện Đại học Y Hà Nội; Nguyễn Lân Hiếu: Bệnh viện Trường Đại học Y Hà Nội, Trường Đại học Y Hà Nội; Nguyễn Thị Minh Lý: Bệnh viện Trường Đại học Y Hà Nội, Trường Đại học Y Hà Nội; Lê Văn Tú: Bệnh viện Đại học Y Hà Nội; Bùi Văn Nhơn: Bệnh viện Đại học Y Hà Nội; Bùi Ngọc Trung: Trung tâm Y tế An Nhơn;
Published: May 30, 2026
Views: 122

Abstract

Atrial septal defect is commonly treated with percutaneous closure due to its high efficacy and safety; however, late complications may still occur. We report a case of a 49-year-old male who underwent closure of a secundum atrial septal defect using a non-polyvinyl alcohol membrane device (Cocoon 40 mm) with initially successful results and no residual shunt during the first two years of follow-up. Four years later, the patient developed palpitations and reduced exercise tolerance. Transthoracic and transesophageal echocardiography revealed multiple left-to-right shunts distributed within the device, suggesting late recanalization. Cardiac multi-slice computed tomography was performed for detailed structural assessment and procedural planning. The patient underwent percutaneous intervention with deployment of an Amplatzer Vascular Plug II within the previous device. Post-procedural imaging demonstrated near-complete closure of the shunts with hemodynamic improvement. This case highlights the importance of long-term follow-up and the role of advanced imaging in guiding management. Percutaneous intervention may be a feasible alternative to surgery in selected cases.

Keywords
Atrial septal defect late recanalization occluder device percutaneous intervention vascular plug

References

1.
Nguyen LH. Transcatheter atrial septal defect closure. In: Clinical Congenital Heart Disease. Hanoi National University Press; 2021:941-970.
2.
King TD, Thompson SL, Steiner C, Mills NL. Secundum atrial septal defect: nonoperative closure during cardiac catheterization. JAMA. 1976;235(23):2506-2509. doi:10.1001/jama.1976.03260490024013.
3.
Chessa M, Carminati M, Butera G, et al. Early and late complications associated with transcatheter occlusion of secundum atrial septal defect. J Am Coll Cardiol. 2002;39(6):1061-1065. doi:10.1016/S0735-1097(02)01711-4.
4.
Koçyildirim E, Kanani M, Bonhoeffer P, Elliott MJ. Amplatzer device embolization: hazards of multiple attempts at catheter retrieval. Anadolu Kardiyol Derg. 2007;7(3):320-323.
5.
Schrale RG, Mitchell AR, Wilson N. Cobra malformation of an Amplatzer device during percutaneous closure of a ventricular septal defect. Eur Heart J. 2007;28(6):698. doi:10.1093/eurheartj/ehl538.
6.
Xiang K, Zhuang H, Wu Q, Tang M, Yang J, Fan C. A rare ultra-long-term complication of occluder recanalization due to spontaneous perforation of polyvinyl alcohol membrane of an atrial septal defect occluder: a case report and review of the literature. Front Cardiovasc Med. 2022;9:926527. doi:10.3389/fcvm.2022.926527.
7.
Berger F, Vogel M, Alexi-Meskishvili V, Lange PE. Comparison of results and complications of surgical and Amplatzer device closure of atrial septal defects. J Thorac Cardiovasc Surg. 1999;118(4):674-678. doi:10.1016/S0022-5223(99)70012-7.
8.
Gurvitz M, Krieger EV, Fuller S, et al. 2025 ACC/AHA/HRS/ISACHD/SCAI guideline for the management of adults with congenital heart disease. J Am Coll Cardiol. 2026;87(7):822-976.
9.
Pham GK. Report on Hospitalized Cardiovascular Patients at the Vietnam National Heart Institute, 1999-2000. Medical Publishing House; 2000.
Percutaneous Intervention for Late Recanalization After Atrial Septal Defect Closure

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Section CA LÂM SÀNG
Category TIM MẠCH CAN THIỆP
Pages 124-129
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