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NGHIÊN CỨU LÂM SÀNG Issue: Số 115 BỆNH MẠCH VÀNH

Usefulness of Mehran risk score in assessing the risk of contrast-induced acute kidney injury in patients who underwent percutaneous coronary intervention in Hue University of Medicine and Pharmacy Hospital

Published: June 30, 2025
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Abstract

Background: To evaluate Mehran risk score in patients who underwent PCI at the Hue University of Medicine and Pharmacy Hospital; and prognosis value of Mehran risk score in risk of Contrast-induced Acute Kidney Injury (CIN-AKI); and kidney function follow up after three months and six months. Patients and methods: Analysing 217 patients who underwent PCI from 01/2020 to 03/2021. Calculating Mehran risk score and analyzing the characteristics related to CIN-AKI and following up the kidney function after three months and six months. Results: Patients with CIN-AKI have an average Mehran risk score of 10.92 ± 6.05, which is significantly higher than patients without CIN-AKI. Multivariate logistic analysis showed that Hypotension, age >75, and diabetes were related significantly to CIN-AKI. Mehran risk score >10 has prognosis for CIN-AKI with a sensitivity of 66.7% and specificity of 88.3%. After three months of follow-up, in patients with CIN-AKI, the kidney function improved, there were three patients with EFGR ml/ph/1.73 m2, and these results were maintained for six months of follow-up. Conclusions: Mehran risk score has prognostic value to assess CIN-AKI in patients who underwent PCI. Among the risk factors, Hypotension, age >75, and diabetes are independent risk factors.

References

1.
Gaziano TA, Prabhakaran D, Gaziano JM. Global Burden of cardiovascular disease. Braunwald’s Heart Disease - A textbook of cardiovascular medicine. 2019; 01-17.
2.
Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation. 2013;127(1):e6-e245. doi:10.1161/CIR.0b013e31828124ad
3.
Almendarez M, Gurm HS, Mariani J Jr, et al. Procedural Strategies to Reduce the Incidence of Contrast-Induced Acute Kidney Injury During Percutaneous Coronary Intervention. JACC Cardiovasc Interv. 2019;12(19):1877-1888. doi:10.1016/j.jcin.2019.04.055
4.
Abellás-Sequeiros RA, Raposeiras-Roubín S, Abu-Assi E, et al. Mehran contrast nephropathy risk score: Is it still useful 10 years later?. J Cardiol. 2016;67(3):262-267. doi:10.1016/j.jjcc.2015.05.007
5.
Wi J, Ko YG, Shin DH, et al. Prediction of Contrast-Induced Nephropathy With Persistent Renal Dysfunction and Adverse Long-term Outcomes in Patients With Acute Myocardial Infarction Using the Mehran Risk Score. Clin Cardiol. 2013;36(1):46-53. doi:10.1002/clc.220602.
6.
Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004;44(7):1393-1399. doi:10.1016/j.jacc.2004.06.068
7.
Rear R, Bell RM, Hausenloy DJ. Contrast-induced nephropathy following angiography and cardiac interventions. Heart. 2016;102(8):638-648. doi:10.1136/heartjnl-2014-306962
8.
Gurm HS, Seth M, Kooiman J, Share D. A novel tool for reliable and accurate prediction of renal complications in patients undergoing percutaneous coronary intervention. J Am Coll Cardiol. 2013;61(22):2242-2248. doi:10.1016/j.jacc.2013.03.026
9.
Liu Y, Tan N, Zhou YL, et al. The contrast medium volume to estimated glomerular filtration rate ratio as a predictor of contrast-induced nephropathy after primary percutaneous coronary intervention. Int Urol Nephrol. 2012;44(1):221-229. doi:10.1007/s11255-011-9910-4
10.
Ni Z, Liang Y, Xie N, et al. Simple pre-procedure risk stratification tool for contrast-induced nephropathy. J Thorac Dis. 2019;11(4):1597-1610. doi:10.21037/jtd.2019.04.69
11.
Sato A, Hoshi T, Kakefuda Y, et al. Effect of the Mehran risk score for the prediction of clinical outcomes after percutaneous coronary intervention. J Cardiol. 2015;66(5):417-422. doi:10.1016/j.jjcc.2014.12.016
12.
Bui XN, Hoang BB, Ho AB. A Study on the Association Between Cardiovascular Risk Factors and MEHRAN Score with Contrast-Induced Acute Kidney Injury. Journal of Clinical Medicine - Hue Central Hospital. 2021(71):01-11.
13.
Kusirisin P, Chattipakorn SC, Chattipakorn N. Contrast-induced nephropathy and oxidative stress: mechanistic insights for better interventional approaches. J Transl Med. 2020;18(1):400. doi:10.1186/s12967-020-02574-8
14.
Abe D, Sato A, Hoshi T, et al. Clinical predictors of contrast-induced acute kidney injury in patients undergoing emergency versus elective percutaneous coronary intervention. Circ J. 2014;78(1):85-91. doi:10.1253/circj.cj-13-0574
15.
Cho E, Ko GJ. The Pathophysiology and the Management of Radiocontrast-Induced Nephropathy. Diagnostics (Basel). 2022;12(1):180. doi:10.3390/diagnostics12010180

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Section NGHIÊN CỨU LÂM SÀNG
Issue Số 115
Category BỆNH MẠCH VÀNH
Pages 99-107
Copyright Holder 2025 Journal of Vietnamese Cardiology