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NGHIÊN CỨU LÂM SÀNG Issue: Số 114

Unipolar electrogram characteristics and predictive ability of target location in ablation of accessory pathways for Wolff - Parkinson - White syndrome

Nguyễn Việt Hưng: Trường Đại học Y Hà Nội; Nguyễn Bá Hiếu: Trường Đại học Y Hà Nội; Trần Tuấn Việt: Trường Đại học Y Hà Nội; Nguyễn Văn Hiếu: Bệnh viện Đại học Y Hà Nội; Phan Đình Phong: Trường Đại học Y Hà Nội;
Published: May 30, 2025
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Abstract

Objective: This study aims to evaluate the predictive ability of unipolar electrograms in identifying target sites for ablation of accessory pathways in the treatment of Wolff-Parkinson-White syndrome.

Results: From June 2023 to August 2024, 70 patients (48 males, 22 females, mean age 37 ± 15) diagnosed with Wolff-Parkinson-White syndrome underwent cardiac electrophysiological studies at the Vietnam National Heart Institute. Unipolar and bipolar electrograms were analyzed at successful and unsuccessful ablation sites. The results showed that unipolar electrogram parameters such as QS wave morphology, accessory pathway potential, and activation time were associated with successful ablation sites. Combining indices from both unipolar and bipolar electrograms can increase the accuracy in identifying target locations.

Conclusion: Unipolar electrogram parameters provide valuable information in identifying the location of accessory pathways in Wolff-Parkinson-White syndrome, with the potential to enhance ablation effectiveness and reduce procedure time

References

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Haïssaguerre M, Dartigues JF, Warin JF, et al. Electrogram patterns predictive of successful catheter ablation of accessory pathways. Value of unipolar recording mode. Circulation. 1991;84(1):188-202. doi:10.1161/01.cir.84.1.188
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Barlow MA, Klein GJ, Simpson CS, et al. Unipolar electrogram characteristics predictive of successful radiofrequency catheter ablation of accessory pathways. J Cardiovasc Electrophysiol. 2000;11(2):146-154. doi:10.1111/j.1540-8167.2000.tb00313.x
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Simmers TA, Hauer RN, Wever EF, et al. Unipolar electrogram models for prediction of outcome in radiofrequency ablation of accessory pathways. Pacing Clin Electrophysiol. 1994;17(2):186-198. doi:10.1111/j.1540-8159.1994.tb01371.x

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Section NGHIÊN CỨU LÂM SÀNG
Issue Số 114