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NGHIÊN CỨU LÂM SÀNG Issue: Số 113

Short-term prognostic value of blood urea concentration in patients with cardiogenic shock due to acute myocardial infarction

Triệu Kim Hoàng: Trường Đại học Y Hà Nội; Nguyễn Lân Hiếu: Bệnh viện Đại học Y Hà Nội;
Published: March 14, 2025
Views: 95
DOI 10.58354/jvc.113.2025.899

Abstract

Objectives: (1)Survey blood urea concentration in patients with cardiogenic shock due to acute myocardial infarction. (2) Find out the short-term (within 30 days) prognostic value of blood urea for major cardiovascular events.

Subjects and methods: Prospective study, cross-sectional description, with 30-day longitudinal follow-up. Cardiogenic shock due to acute myocardial infarction (according to SCAI 2022) at Vietnam Heart Institute and Hanoi Medical University Hospital.

Results: Study of 100 patients followed for 30 days, mortality rate 37%, survival rate 63%. Blood urea cut-off point predicts 30-day mortality in patients with cardiogenic shock due to acute myocardial infarction. Youden-Index with urea level = 8.75 mmol/l, sensitivity 81.1% and specificity 77. 8%. Multivariable Logistic regression analysis urea >8.75 mmol/l is an independent prognostic factor for mortality (OR 5.2, 95% CI 1.3- 20.7, p<0=0.019) and cardiac events main circuit (OR 5.8, 95% CI 1.2-27.4, p=0.026).

Conclude: Admission urea concentration >8.75 mmol/l is closely associated with increased short-term (30-day) mortality and major cardiovascular events in patients with cardiogenic shock due to acute myocardial infarction.

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Section NGHIÊN CỨU LÂM SÀNG
Issue Số 113