Abstract
Objectives: Research on the relationship between red cell distribution width (RDW) index at admission with the burden of thrombosis in the culprit coronary artery and major adverse cardiovascular events (MACE) within 30 days of in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Methods: 208 patients diagnosed ST-segment elevation acute coronary syndrome undergoing successful primary percutaneous coronary intervention from September 2022 to August 2023. Patients were followed up 30 days after discharge and collection about major adverse cardiovascular events including: all-cause death, recurrent myocardial infarction, non-fatal stroke and heart failure hospitalization.
Results: RDW index (OR: 5.51, 95% CI: 2.86 – 10.6, p < 0.001 is an independent predictor of high thrombotic burden in the culprit coronary artery Within 30 days follow-up after discharge, 18 patients had major adverse cardiovascular events (8.65%). The risk of major adverse cardiovascular events within 30 days (adjusted for MI risk factors) in the 2 groups with RDW > 15% and RDW ≤ 15% had a statistically significant difference (HR 2.41; p = 0.024).
Conclusion: Red cell distribution width (RDW) at admission is a parameter that can independently predict high thrombotic burden in the culprit coronary artery and has strong, independent predictive value of major adverse cardiovascular events within 30 days of follow-up in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.