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NGHIÊN CỨU LÂM SÀNG Issue: Issue 99, 2022

Preditive value of TIMI, GRACE, CADILLAC risk scores in patient with ST segment elevation acute myocardial infarction associated diabetes mellitus

Phạm Ngọc Lâm: Đại học Y Hà Nội; Phạm Lê Minh: Viện Tim mạch Việt Nam, Bệnh viện Bạch Mai; Phạm Minh Tuấn: Đại học Y Hà Nội; Viện Tim mạch Việt Nam, Bệnh viện Bạch Mai;
Published: November 1, 2021
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Abstract

Backgroud: Accurate risk stratification has a important role in the management of patient with ST elevation acute myocardial infarction associated diabetes mellitus.
Objectives: To compare the prognostic value of short-term mortality of TIMI, GRACE, CADILLAC scores in patient with ST elevation acute myocardial infarction associated diabetes mellitus
Method study: A prospective cohort
Result: In total, 84 consecutive STEMI patients associated diabetes mellitus were included in the analysis. The mean age of the patients was 67.9 ±10.4. The female patients accounted 35.5%. The obseverd hospital mortality rate was 4.8% (n=4) and the 30-day mortality rate was 8.4% (n=7). The prognostic value of TIMI score for the 30-day mortality (AUC = 0.889, p <0.001) was good accuracy; The prognostic value of GRACE score for the 30-day mortality (AUC = 0.891, p <0.001) was good accuracy; The prognostic value of CADILLAC score for the 30-day mortality (AUC = 0.833, p = 0.004) was good accuracy. There was not statistically significant difference between TIMI score, GRACE score and CADILLAC score in the prognostic value 30-day mortality (Delong test p = 0.317); the sensitivity of GRACE score and TIMI score were 100% higher than that of CADILLAC score but the specificity of CADILLAC score was the highest in these risk score.
Conclusion: TIMI, GRACE and CADILLAC risk stratification scores were equal in prognostic 30-days mortality but specificity of CADILLAC score is higher than two rest score in 30-days mortality.

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