Abstract
Objectives: To investigate factors associated with early in-hospital outcomes of primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) and type 2 diabetes mellitus (T2DM). Methods: A descriptive case-series study was conducted on 78 patients with AMI and T2DM treated at Viet Tiep Friendship Hospital between January 2024 and August 2025. Univariate and multivariate logistic regression analyses were performed to identify factors associated with early outcomes following primary PCI. Results: Of the 78 enrolled patients, 69.2% were male and 66.7% were aged >80 years. Favorable treatment outcomes were observed in 79.5% of patients. Univariate logistic regression analysis demonstrated that heart failure, reduced left ventricular ejection fraction, stenting of the left main coronary artery, stenting of the circumflex artery, and implantation of more than two stents were significantly associated with poor outcomes after primary PCI (OR = 18.06, 95% CI: 4.43-73.56, p = 0.01; OR = 34.05, 95% CI: 7.74-149.78, p = 0.01; OR = 14.07, 95% CI: 1.36-146.27, p = 0.03; OR = 3.77, 95% CI: 1.19-11.96, p = 0.04; and OR = 13.64, 95% CI: 2.34-79.37, p = 0.03, respectively). In multivariate logistic regression analysis, only heart failure and implantation of more than two stents remained independently associated with poor treatment outcomes (OR = 12.52, 95% CI: 2.83-56.31, p = 0.04; OR = 19.82, 95% CI: 1.75-22.47, p = 0.01). Conclusions: Heart failure and implantation of more than two stents were independent factors associated with poor early in-hospital outcomes following primary PCI in patients with T2DM.
