Tạp chí Tim mạch học Việt Nam

Article detail

Article detail description

Home
CA LÂM SÀNG Issue: Số 121 - 2026 BỆNH RỐI LOẠN NHỊP TIM

Late Ventricular Arrhythmia After Coronary Intravascular Lithotripsy for a Severely Calcified LAD Lesion: A Case Report

Nguyễn Văn Hải: Bệnh viện Đa khoa Hồng Ngọc Phúc Trường Minh; Phạm Mạnh Hùng: Trưởng Bộ môn Tim mạch – Trường Đại học Y Hà Nội; Viện trưởng Viện Tim Mạch – Bệnh viện 19-8, Bộ Công an; Chủ tịch Liên đoàn Tim mạch Đông Nam Á; Nguyễn Đình Công: Bệnh viện Đa khoa Hồng Ngọc Phúc Trường Minh; Cao Mạnh Hưng: Bệnh viện Đa khoa Hồng Ngọc Phúc Trường Minh;
Published: May 30, 2026
Views: 95

Abstract

A 79-year-old male with a history of hypertension, diabetes mellitus, dyslipidemia, and two-vessel coronary artery disease, previously treated with percutaneous coronary intervention of the left circumflex artery one month earlier, was admitted for stable angina. Coronary angiography and intravascular ultrasound revealed a long, diffuse, severely calcified lesion in the left anterior descending artery. Lesion preparation with high-pressure balloon dilation was unsuccessful. Therefore, intravascular lithotripsy (IVL) was performed to modify the calcified plaque, followed by successful stent implantation with optimal expansion and TIMI 3 flow. After the procedure, the patient developed chest discomfort accompanied by ventricular ectopy and episodes of non-sustained ventricular tachycardia, with QRS morphology similar to those observed during IVL energy delivery. These arrhythmias persisted for two days and were associated with dynamic elevation of cardiac biomarkers, while hemodynamic status remained stable. Symptoms and arrhythmias improved with nitrate and amiodarone therapy. This case highlights that ventricular arrhythmias may not only occur during IVL but can also develop and persist after the procedure, underscoring the importance of close post-procedural monitoring in clinical practice.

Keywords
IVL Ventricular arrhythmias Coronary artery calcification Percutaneous coronary intervention

References

1.
Barbato E, Shlofmitz E, Milkas A, Shlofmitz RA, Azzalini L, Colombo A. State of the art: evolving concepts in the treatment of heavily calcified and undilatable coronary stenoses: from debulking to plaque modification. EuroIntervention. 2021;17(6):e403-e415. doi:10.4244/EIJ-D-21-00089.
2.
Ali ZA, Nef H, Escaned J, et al. Safety and effectiveness of coronary intravascular lithotripsy for treatment of severely calcified coronary stenoses: the Disrupt CAD II study. Circ Cardiovasc Interv. 2019;12(10):e008434. doi:10.1161/CIRCINTERVENTIONS.119.008434.
3.
Hill JM, Kereiakes DJ, Shlofmitz RA, et al. Intravascular lithotripsy for treatment of severely calcified coronary artery disease. J Am Coll Cardiol. 2020;76(22):2635-2646. doi:10.1016/j.jacc.2020.09.603.
4.
Brinton TJ, Ali ZA, Hill JM, et al. Feasibility of shockwave coronary intravascular lithotripsy for the treatment of calcified coronary stenoses. Circulation. 2019;139(6):834-836. doi:10.1161/CIRCULATIONAHA.118.036531.
5.
Wilson SJ, Spratt JC, Hill JM, et al. Coronary intravascular lithotripsy is associated with a high incidence of ventricular ectopy and asynchronous cardiac pacing. EuroIntervention. 2020;15(16):e1429-e1431. doi:10.4244/EIJ-D-19-00601.
6.
Niccoli G, Burzotta F, Galiuto L, Crea F. Myocardial no-reflow in humans. J Am Coll Cardiol. 2009;54(4):281-292. doi:10.1016/j.jacc.2009.03.054.
7.
Rosenbaum MB, Blanco HH, Elizari MV, Lazzari JO, Davidenko JM. Electrotonic modulation of the T wave and cardiac memory. Am J Cardiol. 1982;50(2):213-222. doi:10.1016/0002-9149(82)90169-2.
8.
Tzikas A, Panoulas VF, Karvounis H, et al. Ventricular ectopy during coronary intravascular lithotripsy. Catheter Cardiovasc Interv. 2021;98(6):E825-E828. doi:10.1002/ccd.29754.
Late Ventricular Arrhythmia After Coronary Intravascular Lithotripsy for a Severely Calcified LAD Lesion: A Case Report

Files

Article Views95
Document Views7
Downloads2
Section CA LÂM SÀNG
Category BỆNH RỐI LOẠN NHỊP TIM
Pages 114-123
Copyright Holder 2026 Tạp chí Tim mạch học Việt Nam